Hindered Non-Standard Amino Acid的微波合成用

更新時間：2012-06-29 點擊次數(shù)：2053

INTRODUCTION
The N-α-Fmoc-α-aminoisobutyric acid derivative （Aib） is a difficult derivative for coupling in SPPS due to its second methyl group on the α-carbon that interferes with the coupling reaction （Figure 1）. However, it can be found in a number of biologically relevant compounds, particularly fungal-derived peptide antibiotics such as alamethicin, so methods to successfully couple the Aib amino acid need to be developed. The use of microwave enhanced synthesis helps to drive difficult reactions like those containing the Aib amino acid to completion.

Figure 1: N-α-Fmoc-α-aminoisobutyric acid

Liberty 全自動流動微波多肽合成系統(tǒng)

更多詳情，請培安公司：
：北京：上海：成都：廣州：
: sales@pynnco.com ：www.pynnco.com

上一篇：Peptoids的微波合成
下一篇：CEM用紫外監(jiān)測配件改進了復(fù)雜多肽類的合成

亚洲一本大道综合网|国产毛片一区二区视频|精品综合久久久久久98|亚洲最大国产成人综合网站|精品人妻大白屁股白浆优播|精品一区二区在线观看国产|亚洲欧美中文日韩v在线观看|囯产精品久久永久免费无码网站

Hindered Non-Standard Amino Acid的微波合成用